Humanitarian professionals working in complex environments face increasing threats and attacks that endanger their lives, violate international humanitarian law, and jeopardize the consistent and effective delivery of emergency relief to populations in need. In light of these issues, this paper explores challenges and opportunities related to the predominant organizational approaches to the protection of aid workers in complex and insecure environments, and highlights often overlooked disparities in the risks faced by different groups of humanitarian professionals based on their status as national or international staff, gender, and organizational affiliation. It argues that insufficient attention has thus far been paid to the significance of these disparities and their implications for operational security and effectiveness. Furthermore, it highlights significant fragmentation and gaps in the protection of aid workers under international law and the culture of impunity prevailing for perpetrators of such attacks. It then examines the recent trends in humanitarian security management — namely, acceptance, protection, and deterrence. Finally, it offers reflections for the humanitarian community on improving the state of knowledge, practice and law with regard to the protection of humanitarian professionals.